It is commonly used after surgery. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Medication Guide of Ketorolac. Ketorolac ophthalmic (for the eye) is used to relieve eye itching caused by seasonal allergies. Review keterolak of: Effect of intracameral phenylephrine 1.0%–ketorolac 0.3% on postoperative cystoid macular edema, iritis, pain, and photophobia after cataract surgery Visco D, Bedi R. Ketorolac should not be used for minor or chronic painful conditions.. Ketorolac ophthalmic is also …. Trade Name. The inhibition of COX-2, up-regulated at sites of inflammation, prevents conversion of arachidonic acid to pro-inflammatory prostaglandins. Ketorolac, a non-selective inhibitor of the cyclo-oxygenase (COX) enzyme, prevents the synthesis of prostaglandins and thromboxanes from arachidonic acid. The biological activity of ketorolac tromethamine is associated with the S-form. Ketorolac tromethamine is a racemic mixture of [-]S and [+]R ketorolac tromethamine.